St. Charles Borromeo Church, located at 601 N. Fourth Street in St. Charles, Missouri, is named after Saint Charles Borromeo (Carlo Borromeo) of the Counter-Reformation period and is the third oldest parish in the St. Louis Archdiocese. The original church, dedicated in 1791, was moved to its current location in 1869. The brick church’s structure, damaged during a storm in 1915, was reconstructed in 1916.